VyndaMx ® 61 mg

By Pfizer Products India Private Limited, India

Pack of 30 soft capsules (3 strips of 10 soft gelatin capsules each)(3X10)

Delivery in 48 - 72 hrs

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VyndaMx ® 61 MG Description

Tafamidis is indicated for the treatment of wild-type or hereditary transthyretin amyloidosis in adult patients with cardiomyopathy (ATTR-CM)....Treatment should be initiated under the supervision of a cardiologist knowledgeable in the management of patients with amyloidosis or cardiomyopathy.

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Product Summary
Price ₹120000
Contains 61 mg of micronized tafamidis

Uses of VyndaMx 60mg

The soft capsules should be swallowed whole and not crushed or cut. Tafamidis may be taken with or without food.

Special warnings and precautions for use of VyndaMx 60mg

  • Women of childbearing potential should use appropriate contraception when taking tafamidis and continue to use appropriate contraception for 1-month after stopping treatment with tafamidis.
  • Tafamidis should be added to the standard of care for the treatment of patients with transthyretin amyloidosis. Physicians should monitor patients and continue to assess the need for other therapy, including the need for organ transplantation, as part of this standard of care. As there are no data available regarding the use of tafamidis in organ transplantation, tafamidis should be discontinued in patients who undergo organ transplantation.
  • Increase in liver function tests and decrease in thyroxine may occur.
  • This medicinal product contains no more than 44 mg sorbitol in each capsule. Sorbitol is a source of fructose.
  • The additive effect of concomitantly administered products containing sorbitol (or fructose) and dietary intake of sorbitol (or fructose) should be taken into account.
  • The content of sorbitol in medicinal products for oral use may affect the bioavailability of other medicinal products for oral use administered concomitantly.

Mechanism of Action

Tafamidis is a selective stabiliser of TTR. Tafamidis binds to TTR at the thyroxine binding sites, stabilising the tetramer and slowing dissociation into monomers, the rate-limiting step in the amyloidogenic process.